EasyCyte flow cytometers use compact microcapillary technology powerful enough to run complex assays. Fluidics enable a self-aligning flow cell that can be removed for cleaning. Lasers available in virtually any combination mean that best excitation and emission channels can be chosen. The microcapillary allows direct sampling by aspiration. The flow cell is self-analyzing, and can be easily removed for cleaning. The system is broadly applicable for measuring a wide variety of cells and particles.